A protein that is involved in the wound healing process, it is found in blood plasma and in the extracellular matrix of the skin where it helps bind cellular components such as collagen. It is used in skin substitutes for treatment of burns where it stimulates the wound healing process. Found in skin care formulations for its antimicrobial and skin repair properties. There is no evidence that applying fibronectin topically enhances fibronectin in the skin.

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